How frogs resist their own toxins
The phantasmal poison frog, Epipedobates anthonyi, is the original source of epibatidine, discovered by John Daly in 1974. In fact, epibatidine is named for...
Our collaborative paper on genetic mechanisms of toxin resistance in poison frogs has been published in Science. Lead author extraordinaire Becca Tarvin's work shows that frogs have come up with multiple ways to resist the toxin epibatidine.
Co-authors Becca and Juan came to our lab (when we were at Harvard) to sequence the transcriptomes of 26 poison frog species. Becca used the ion channel information from our major sequencing efforts for her studies on ion channel evolution in poison frogs.